Holger Proksich, PhD

Holger Proksich, PhD

Holger Prokisch, PhD, is head of the research group “Genetics of Mitochondrial Disorders” at the Institute of Human Genetic of the Technical University Munich and of the Helmholtz Zentrum München. He has longstanding experience in the molecular analysis of mitochondrial disorders. His research focus seeks to understand genetic variation in both rare and common disorders leading to mitochondria-related dysfunction. He was very successful in integrating genomic approaches with detailed functional biochemical investigations. By applying WES, his group has contributed to the discovery of more than 50 novel disease genes and to the diagnosis of more than 1,000 patients. In his work, Dr. Prokisch undertakes genomic, proteomic, metabolomic, and transcriptomic studies and accomplishes computational analysis to produce a comprehensive picture of mitochondrial dysfunction. Dr. Prokisch coordinates two Eurasian networks for mitochondrial disorders (GENOMIT and PerMiM).