Detailed Scientific Program

Detailed Scientific Program

Monday, June 14, 2021

TimeSessionSpeaker
13:30Login/Buffer time
14:10 - 15:40General Session 1:
Gene Fusions: An Emerging Target in Cancer
Diagnostics and Treatment
Moderator: Marina Nikiforova, MD
Co-moderator: Sabine Merkelbach-Bruse
14:10 - 15:40ESMO Guidelines and TRK Algorithm in CancerFrédérique Penault-Llorca
14:10 - 15:40High Scale Sequencing (RNA-Seq) for Fusion DetectionFelix Sahm, MD, PhD
Break/Transition
16:00 - 17:00Industry Symposium
Break/Transition
17:20 - 18-20Breakout Session 1:
Future of Molecular Diagnostics in
Clinical Oncology
Moderator: Marina Nikiforova, MD
Co-moderator: Sabine Merkelbach-Bruse
17:20 - 18-20DNA Methylation Based Tumor ClassificationAndreas von Deimling, MD
17:20 - 18-20Molecular Screening of Advanced Cancer PatientsMarjolijn Ligtenberg, PhD
Parallel sessions
17:20 - 18:20Breakout Session 2:
Exploring Informatics:
Quality Metrics to
Artificial Intelligence
Moderator: Elaine Lyon, PhD
Co-moderator: Matthew Lebo
17:20 - 18:20A Deep Dive into Quality Metrics – From Sample to ReportHoney V Reddi, PhD, FACMG
17:20 - 18:20Artificial Intelligence, how to assess whether it can work,
it does work and it is worth it!
Frederico Cabitza, PhD
Break/Transition
18:45 - 19:30Parrallel Industry Symposium
Parallel sessions
18:45 - 19:30Parrallel Industry Symposium
Break/Transition
19:50 - 20:50General Session 5:
Innate Immunity, Inflammation and Cancer:
Double Edged Swords
Moderator: Massimiliano M. Corsi Romanelli, MD, PhD
Co-moderator: Francesco Curcio
19:50 - 20:50Innate Immunity, Inflammation and Cancer:
Double Edged Swords
Alberto Mantovani, MD

Tuesday, June 15, 2021

TimeSessionSpeaker
12:00 - 13:40Special Session (TBA)
Break/Transition
14:00 - 14:45Parrallel Industry Symposium
Parallel sessions
14:00 - 14:45Parrallel Industry Symposium
Break/Transition

15:10–16:40

General Session 2:
Findings in Population Studies:
A European View
Moderator: Matthew Lebo, PhD
Co-moderator: Tong Zhang

15:10–16:40

Genetic and Clinical Risk of Common
Complex Diseases in FinnGen Study
Samuli Ripatti, PhD

15:10–16:40

Return of Data Activities in Population-based Biobank:
Current Experience and Implications for Personalized
Prevention on a National Scale
Neeme Tõnisson, PhD
Break/Transition
17:00 - 18:00Industry Symposium
Break/Transition

18:20 - 19:20

Breakout Session 3:
Approaches to Cutting
Edge Somatic Testing
Moderator: Matthew Lebo, PhD
Co-moderator: Tong Zhang

18:20 - 19:20

TMB ApproachesAlbrecht Stenzinger, MD

18:20 - 19:20

Liquid Biopsy/cfDNA InformaticsNitzan Rosenfeld
19:30 - 20:00Meet the Speakers: Informatics
Parallel sessions

18:20 - 19:20

Breakout Session 4:
Quality Assurance in
Molecular Testing
Moderator: Hubert G. Niesters, PhD
Co-moderator: Marina Nikiforova, MD

18:20 - 19:20

TBAPaul Wallace

18:20 - 19:20

QA in Cancer Diagnostics:
Consistency and Reproducibility of
Next-generation Sequencing in Cytopathology
Giancarlo Troncone, MD, PhD
19:30 - 20:00Meet the Speakers: Infectious Diseases

Wednesday, June 16, 2021

TimeSessionSpeaker
14:00 - 14:45Parrallel Industry Symposium
Parallel sessions
14:00 - 14:45Parrallel Industry Symposium
Break/Transition
15:10 - 16:40General Session 3:
Metagenomics and NGS
in Clinical Microbiology
Moderator: Hubert G. Niesters, PhD
15:10 - 16:40Using NGS in Looking for PathogensCharles Chiu, MD, PhD
15:10 - 16:40Use of NGS in Infection Control and
the Detection of Resistance Genes
John Rossen, PhD, MSc
Break/Transition
17:00 - 18:00Industry Symposium
Break/Transition
18:20 - 19:20Breakout Session 5:
Translating Cancer Genomics
into Precision Medicine
with Artificial Intelligence
Moderator: Marina Nikiforova, MD
Co-moderator: Sabine Merkelbach-Bruse
18:20 - 19:20Translating Cancer Genomics into
Precision Medicine with Artificial Intelligence
Olivier Elemento, PhD
19:30 - 20:00Meet the Speakers: Solid Tumours
Parallel sessions
18:20 - 19:20Breakout Session 6:
Germline Mutations Predisposing to
Hematological Malignancies
Moderator: Valentina Nardi, MD
18:20 - 19:20Genetic Predisposition to Myeloid NeoplasmsCharlotte Niemeyer
18:20 - 19:20When Mild Inherited Disorders
Underlie the Risk of Acquiring
Life-threatening Diseases
Carlo Balduini

Thursday, June 17, 2021

TimeSessionSpeaker
14:00 - 14:45Parrallel Industry Symposium
Parallel sessions
14:00 - 14:45Parrallel Industry Symposium
Break/Transition

15:10–16:40

General Session 4:
STAT: Critical Care Genomics
Moderator: Elaine Lyon, PhD

15:10–16:40

Indications and Utility of Rapid Genomes in ICU SettingsStephen Kingsmore

15:10–16:40

Clinical Utility of Genomic Sequencing
in a Newbornand Neonatal Intensive Care Settings
Christine M Eng, MD
Break/Transition
17:00 - 18:00Industry Symposium
Break/Transition
18:20 - 19:20Breakout Session 7:
Liquid Biopsies
for Lymphomas
Moderator: Valentina Nardi, MD
18:20 - 19:20Liquid Biopsy for Disease Monitoring in B-cell LymphomaGianluca Gaidano, MD, PhD
19:30 - 20:00Meet the Speakers: Genetics
Parallel sessions
18:20 - 19:20Breakout Session 8:
What's Next in Clinical Genomics?
Supplementing Genome/Exome
Analysis
Moderator: Elaine Lyon, PhD
18:20 - 19:20The Diagnosis of Mendelian
Disorders by an Integrative
“multi-omic” Approach
Holger Proksich, PhD
18:20 - 19:20Identification of Hidden
Structural Variants with Long-Read
Sequencing and Genome Imaging
Alexander Hoischen, PhD
19:30 - 20:00Meet the Speakers: Hempath

Friday, June 18, 2021

TimeSessionSpeaker
14:00 - 14:45Parrallel Industry Symposium
Parallel sessions
14:00 - 14:45Parrallel Industry Symposium
Break/Transition

15:10–16:10

General Session 6:
SIPMeT Session -
Deregulation & Targeting in Cancer

Moderator: Massimiliano M. Corsi Romanelli, MD, PhD
Co-moderator: Francesco Curcio

15:10–16:10

Targeting Epigenome in Cancer

Lucia Altucci, MD, PhD

15:10–16:10

Deregulation of Hedgehog Signaling in Cancer:
Targeting Epigenetic and Metabolic Vulnerabilities

Gianluca Canettieri, MD, PhD

Break/Transition

16:30–17:30

General Session 7:
COVID 19

Moderator: Massimiliano M. Corsi Romanelli, MD, PhD
Co-moderator: Hubert G. Niesters, PhD

16:30–17:30

TBA

Sergio Abrignani

16:30–17:30

TBA

Felix Drexler

Break/Transition
17:50 - 18:50Industry Symposium
TimeSessionSpeaker
13:30Login/Buffer time
14:10 - 15:40General Session 1:
Gene Fusions: An Emerging Target in Cancer
Diagnostics and Treatment
Moderator: Marina Nikiforova, MD
Co-moderator: Sabine Merkelbach-Bruse
14:10 - 15:40ESMO Guidelines and TRK Algorithm in CancerFrédérique Penault-Llorca
14:10 - 15:40High Scale Sequencing (RNA-Seq) for Fusion DetectionFelix Sahm, MD, PhD
Break/Transition
16:00 - 17:00Industry Symposium
Break/Transition
17:20 - 18-20Breakout Session 1:
Future of Molecular Diagnostics in
Clinical Oncology
Moderator: Marina Nikiforova, MD
Co-moderator: Sabine Merkelbach-Bruse
17:20 - 18-20DNA Methylation Based Tumor ClassificationAndreas von Deimling, MD
17:20 - 18-20Molecular Screening of Advanced Cancer PatientsMarjolijn Ligtenberg, PhD
Parallel sessions
17:20 - 18:20Breakout Session 2:
Exploring Informatics:
Quality Metrics to
Artificial Intelligence
Moderator: Elaine Lyon, PhD
Co-moderator: Matthew Lebo
17:20 - 18:20A Deep Dive into Quality Metrics – From Sample to ReportHoney V Reddi, PhD, FACMG
17:20 - 18:20Artificial Intelligence, how to assess whether it can work,
it does work and it is worth it!
Frederico Cabitza, PhD
Break/Transition
18:45 - 19:30Parrallel Industry Symposium
Parallel sessions
18:45 - 19:30Parrallel Industry Symposium
Break/Transition
19:50 - 20:50General Session 5:
Innate Immunity, Inflammation and Cancer:
Double Edged Swords
Moderator: Massimiliano M. Corsi Romanelli, MD, PhD
Co-moderator: Francesco Curcio
19:50 - 20:50Innate Immunity, Inflammation and Cancer:
Double Edged Swords
Alberto Mantovani, MD
TimeSessionSpeaker
12:00 - 13:40Special Session (TBA)
Break/Transition
14:00 - 14:45Parrallel Industry Symposium
Parallel sessions
14:00 - 14:45Parrallel Industry Symposium
Break/Transition

15:10–16:40

General Session 2:
Findings in Population Studies:
A European View
Moderator: Matthew Lebo, PhD
Co-moderator: Tong Zhang

15:10–16:40

Genetic and Clinical Risk of Common
Complex Diseases in FinnGen Study
Samuli Ripatti, PhD

15:10–16:40

Return of Data Activities in Population-based Biobank:
Current Experience and Implications for Personalized
Prevention on a National Scale
Neeme Tõnisson, PhD
Break/Transition
17:00 - 18:00Industry Symposium
Break/Transition

18:20 - 19:20

Breakout Session 3:
Approaches to Cutting
Edge Somatic Testing
Moderator: Matthew Lebo, PhD
Co-moderator: Tong Zhang

18:20 - 19:20

TMB ApproachesAlbrecht Stenzinger, MD

18:20 - 19:20

Liquid Biopsy/cfDNA InformaticsNitzan Rosenfeld
19:30 - 20:00Meet the Speakers: Informatics
Parallel sessions

18:20 - 19:20

Breakout Session 4:
Quality Assurance in
Molecular Testing
Moderator: Hubert G. Niesters, PhD
Co-moderator: Marina Nikiforova, MD

18:20 - 19:20

TBAPaul Wallace

18:20 - 19:20

QA in Cancer Diagnostics:
Consistency and Reproducibility of
Next-generation Sequencing in Cytopathology
Giancarlo Troncone, MD, PhD
19:30 - 20:00Meet the Speakers: Infectious Diseases
TimeSessionSpeaker
14:00 - 14:45Parrallel Industry Symposium
Parallel sessions
14:00 - 14:45Parrallel Industry Symposium
Break/Transition
15:10 - 16:40General Session 3:
Metagenomics and NGS
in Clinical Microbiology
Moderator: Hubert G. Niesters, PhD
15:10 - 16:40Using NGS in Looking for PathogensCharles Chiu, MD, PhD
15:10 - 16:40Use of NGS in Infection Control and
the Detection of Resistance Genes
John Rossen, PhD, MSc
Break/Transition
17:00 - 18:00Industry Symposium
Break/Transition
18:20 - 19:20Breakout Session 5:
Translating Cancer Genomics
into Precision Medicine
with Artificial Intelligence
Moderator: Marina Nikiforova, MD
Co-moderator: Sabine Merkelbach-Bruse
18:20 - 19:20Translating Cancer Genomics into
Precision Medicine with Artificial Intelligence
Olivier Elemento, PhD
19:30 - 20:00Meet the Speakers: Solid Tumours
Parallel sessions
18:20 - 19:20Breakout Session 6:
Germline Mutations Predisposing to
Hematological Malignancies
Moderator: Valentina Nardi, MD
18:20 - 19:20Genetic Predisposition to Myeloid NeoplasmsCharlotte Niemeyer
18:20 - 19:20When Mild Inherited Disorders
Underlie the Risk of Acquiring
Life-threatening Diseases
Carlo Balduini
TimeSessionSpeaker
14:00 - 14:45Parrallel Industry Symposium
Parallel sessions
14:00 - 14:45Parrallel Industry Symposium
Break/Transition

15:10–16:40

General Session 4:
STAT: Critical Care Genomics
Moderator: Elaine Lyon, PhD

15:10–16:40

Indications and Utility of Rapid Genomes in ICU SettingsStephen Kingsmore

15:10–16:40

Clinical Utility of Genomic Sequencing
in a Newbornand Neonatal Intensive Care Settings
Christine M Eng, MD
Break/Transition
17:00 - 18:00Industry Symposium
Break/Transition
18:20 - 19:20Breakout Session 7:
Liquid Biopsies
for Lymphomas
Moderator: Valentina Nardi, MD
18:20 - 19:20Liquid Biopsy for Disease Monitoring in B-cell LymphomaGianluca Gaidano, MD, PhD
19:30 - 20:00Meet the Speakers: Genetics
Parallel sessions
18:20 - 19:20Breakout Session 8:
What's Next in Clinical Genomics?
Supplementing Genome/Exome
Analysis
Moderator: Elaine Lyon, PhD
18:20 - 19:20The Diagnosis of Mendelian
Disorders by an Integrative
“multi-omic” Approach
Holger Proksich, PhD
18:20 - 19:20Identification of Hidden
Structural Variants with Long-Read
Sequencing and Genome Imaging
Alexander Hoischen, PhD
19:30 - 20:00Meet the Speakers: Hempath
TimeSessionSpeaker
14:00 - 14:45Parrallel Industry Symposium
Parallel sessions
14:00 - 14:45Parrallel Industry Symposium
Break/Transition

15:10–16:10

General Session 6:
SIPMeT Session -
Deregulation & Targeting in Cancer

Moderator: Massimiliano M. Corsi Romanelli, MD, PhD
Co-moderator: Francesco Curcio

15:10–16:10

Targeting Epigenome in Cancer

Lucia Altucci, MD, PhD

15:10–16:10

Deregulation of Hedgehog Signaling in Cancer:
Targeting Epigenetic and Metabolic Vulnerabilities

Gianluca Canettieri, MD, PhD

Break/Transition

16:30–17:30

General Session 7:
COVID 19

Moderator: Massimiliano M. Corsi Romanelli, MD, PhD
Co-moderator: Hubert G. Niesters, PhD

16:30–17:30

TBA

Sergio Abrignani

16:30–17:30

TBA

Felix Drexler

Break/Transition
17:50 - 18:50Industry Symposium